ABSTRACT
We aimed to review the records of cancer and kidney transplant patients of out of 1135 COVID-19 patients, who were referred to our hospital (Valiasr) in Zanjan, from March 16th, 2020, to June 11th, 2020. This was single-center, historical cohort study. Patients were divided into different subgroups and compared of disease outcomes. The only predictor of death was lactate dehydrogenase (LDH). The rate of red cell distribution width (RDW) in patients with active cancer was higher than kidney transplant patients and was statistically significant. There was no statistically significant difference in mortality between active and non-active cancer groups. Female sex and low SpO2 has increased the chances of ICU admission. Patients with active cancer generally have severe and more complicated disease and RDW can be a predictable option.
ABSTRACT
BACKGROUND: Recent studies have focused on the incidence rate and pattern of meningoencephalitis in the coronavirus disease 2019 (COVID-19). AIM: This study aims to shed more light on the CSF pattern and clinical characteristics of meningoencephalitis COVID-19 patients in Zanjan, Iran. METHODS: Nine cases of laboratory and imaging confirmed COVID-19 were admitted to Valiasr Hospitals in Zanjan, Iran. Data were collected from May 20, 2020 to June 20, 2020. RESULTS: All the nine patients had positive RT-PCR COVID-19 and Pulmonary involvement who underwent Lumbar puncture and analysis, but despite neurological symptoms, the RT-PCR of CSF for COVID-19 was negative. CONCLUSION: Although we did not have any cases of positive RT-PCR for COVID-19 in lumbar puncture specimens, the justification of neurological symptoms in patients can be the transient presence of the virus in the CSF, and inflammation or autoimmune response caused by the virus, so more studies are needed to determine the cause of neurogenic symptoms.